MoCA er en mere kognitivt krævende test end MMSE, hvilket ses ved at både personer uden demens, personer med MCI og personer med demens opnår relativt lavere scores på MoCA end på MMSE (Nasreddine 2005). Alternating Trail Making: Administration: The examiner instructs the subject: 'Please draw a line going from a number to a letter in ascending order. MoCA opgøres i råscores, der sammentælles til en score, der går fra 0 til 30 med 30 som det ‘bedste’ (fejlfri) resultat. This better discrimination was more evident in the more educated group.Īddenbrooke’s Cognitive Examination Alzheimer disease Memory Impairment Screen Mini-Mental State Examination Montreal Cognitive Assessment Neuropsychological assessment Rowland Universal Dementia Assessment Scale Screening. The total possible score is 30 points a score of 26 or above is considered normal. The ACE-III achieved the highest diagnostic accuracy.
Implementing normative data improved the diagnostic accuracy of the ACE-III but not that of the other tests. All tests, especially the ACE-III, conveyed a higher diagnostic accuracy in patients with full primary education than in the less educated group. Memory scores of the ACE-III and of the RUDAS showed a better diagnostic accuracy than those of the MMSE and of the MoCA. The Mini-ACE score from the ACE-III showed the highest diagnostic capacity (area under the curve 0.939). The area under the curve was 0.897 for the ACE-III, 0.889 for the RUDAS, 0.874 for the MMSE, 0.866 for the MIS, and 0.856 for the MoCA. The diagnostic properties of the following tests were compared: Mini-Mental State Examination (MMSE), Addenbrooke's Cognitive Examination III (ACE-III), Memory Impairment Screen (MIS), Montreal Cognitive Assessment (MoCA), and Rowland Universal Dementia Assessment Scale (RUDAS).Īll tests yielded high diagnostic accuracy, with the ACE-III achieving the best diagnostic properties. Therefore, the MoCA is likely an appropriate choice of screening instrument in this context, so long as examiners also assess relevant aspects of validity of the presentation. We conducted a prospective and cross-sectional study of 92 patients with mild AD and of 68 healthy controls from our Department of Neurology. When only valid data were examined, MoCA scores were associated with tests sensitive to brain injury (e.g., TMT Parts A and B). Our aim was to evaluate and compare the diagnostic properties of 5 screening tests for the diagnosis of mild Alzheimer disease (AD).